Animal Biology Laboratory Facilities and Management
Animal Biology Facilities and Management
The animal biology laboratory should carefully consider the walking routes of pharma machinery personnel, items, supply equipment, and animal transportation, and try to eliminate or reduce pollution. It is better to use double corridors in the layout of the facility; it should be based on the type and variety of animals. , strain, body size, birth...
Text Labels: Animal Biology , Facilities and Management
Animal Biology Facilities and Management
The animal biology laboratory should carefully consider the walking routes of laboratory personnel, items, supply equipment, and animal transportation, and try to eliminate or reduce pollution. It is better to use double corridors in the layout of the facility; it should be based on the type and variety of animals. , strain, body size, living habits, experimental purposes, etc., select biological safety cabinets with corresponding biological safety protection levels, dedicated to experimental animals, and in line with the corresponding national standards, as well as animal feeding, animal experiments, cleaning and decontamination, sterilization and other facilities and equipment; the planning and design of the laboratory should consider in detail the layout, function division, access control, and the arrangement of the movement routes of personnel and items, all of which should meet the needs of the animals used in the experiment; the exhaust air from the animal room cannot be recycled. , the air containing aerosols in the animal room should be filtered by HEPA before it can be discharged; the environmental indicators of the animal laboratory should comply with the regulations of the animal environment and facilities.
Each animal pharma machinery biosafety level includes four coordinating measures: standard microbiological practices, special operating practices, safety equipment, and laboratory facilities. There are different treatment methods according to different levels. The higher the level, the more The four cooperating measures are more stringent. The first-level animal laboratory does not require special first-level and second-level isolation equipment and facilities. The animal pharma machinery is separated from the general passage in the building; the experiment can be operated on the laboratory bench, and the use of approved isolation equipment is not required. The personnel pass the professional training related to the room, and are supervised and managed by scientific researchers with experience in microbiology or related disciplines. The animal breeding room should be isolated from other areas in the building; the door of the breeding room should have a viewing window, open inward, and the opened door should be able to close automatically, and can be locked when needed; the working surface of the breeding room should be waterproof and easy to extinguish It is not suitable to install windows. If windows are installed, all windows should be sealed; the strength of the enclosure structure should be suitable for the species of animals raised; depth; the air exhausted from the animal laboratory shall not be recycled; a sink or hand cleaning device should be set up, which should be set at the exit; the indoor air pressure in the animal breeding room should be controlled to a negative pressure; experimental animal breeding cages or guardrails should be set up , in addition to safety requirements, animal welfare requirements should also be considered. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for animal biological laboratories and clean rooms.
Animal biosafety second-level laboratory, personnel must undergo special training in handling microorganisms, and be guided and managed by competent professionals; outsiders are restricted from entering the laboratory during work; some aerosols or splashes are produced. Work in biological safety cabinets or other physical isolation equipment; take high precautions against contaminated sharps. Facilities and equipment requirements: It should meet the requirements of the first-level protection level of animal biosafety; the animal breeding room should be equipped with a buffer room at the entrance and exit; a non-manual sink or hand cleaning device should be set up, which should be set at the exit; high pressure should be installed in the adjacent area Steam sterilizer; activities that may generate harmful aerosols should be carried out in the safety isolation device, and the exhaust gas should be filtered by HEPA filter and discharged; the indoor air pressure in the animal breeding room should be controlled to negative pressure, and the gas should be directly discharged to other places. Outside the building; the external air outlet of the laboratory should be at least 2m higher than the top of the building where the laboratory is located, and it should be designed to prevent wind, rain and insects, but it should not affect the air discharge over the air; the sewage should be sterilized and dealt with. Sterilization effects are monitored to ensure discharge requirements are met.
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