Clean workshop purification and decoration graphic design basis In the design of clean workshop, each equipment considers a certain position, including the position of the equipment itself, the position of operation, the position of equipment, the position of equipment maintenance and disassembly, and the safety of equipment and equipment, equipment and buildings distance. layout should be considered to create conditions for operators to manage multiple equipment or multiple types of equipment. It should not be too tight or too loose. It should be symmetrical and compact as much as possible, neatly arranged, and make full use of space. The automatic monitoring instruments of the equipment should be controlled centrally, and the valve control should be centralized as much as possible to facilitate the operation of workers. To meet the requirement that the pharma machinery can enter and exit the workshop smoothly, through the equipment on the floor, hoisting holes should be set on the floor. Consider the maintenance and dismantling of equipment in the clean workshop, as well as the lifting and transportation equipment required to transport materials; any heavy equipment or equipment that will generate severe vibrations during operation should be arranged on the bottom floor of the workshop as much as possible to reduce the load on the workshop floor. And for equipment that vibrates violently, its foundation shall not be connected with the columns and walls of the building, so as not to affect the safety of the building. The equipment layout should avoid the columns and main beams of the building. All operating platforms in the workshop must be considered in a unified manner to avoid random repetition of platform pillars, which will affect the appearance of the workshop, production operations and maintenance. 1. Layout plan of the clean workshop The production category of the pharmaceutical cleanroom is Class C, the fire resistance level is two-level structure, the form is a single-layer frame, and the floor height is 5m; the clean control area is provided with a suspended ceiling; the ceiling height is 2.70m; the one-step granulation room is partially raised to 3.5m. The personnel and materials in the workshop enter the clean area through their own private passages, and there is no cross between the flow of people and the logistics. There are three main entrances and exits of the whole workshop. One is the outflow of people, that is, people enter the pharmaceutical cleanroom from the hall through changing clothes, and then enter the clean production area after washing their hands and cleaning clothes, and hand disinfection; one is the population of raw materials, that is, the raw materials pass through The unpacking package is sent in through the transfer window; the other place is the export of finished products. The internal layout of the workshop mainly includes processes such as wet granulation, drying, granulation, total mixing, filling, polishing, aluminum-plastic inner packaging, and outsourcing. 2. Treatment of dust in the clean workshop For the positions of crushing, sieving, granulating, drying, granulating, mixing, and filling with a large amount of dust, it is necessary to design necessary dust-catching and dust-removing devices. Both return air and exhaust air are set in the dust-generating chamber, and the exhaust air system is interlocked with the corresponding air supply system, that is, the exhaust air system can only be opened after the stacking air system is running, so as to avoid incorrect operation and ensure that the clean area is relatively normal to the outside. pressure. When the process produces dust, open the dust collector and close the return air; when no dust is generated, open the return air and close the exhaust air. 3. For posts with large heat dissipation and moisture dissipation, such as heat exhaustion, moisture exhaustion, untreated pulp mixing, container cleaning, etc. in the workshop, in addition to designing a moisture removal device, a front room is also set up to avoid the large amount of moisture dissipation and heat dissipation. Affects the operating and ambient air conditioning parameters of adjacent clean rooms. The drying room is a process that generates moisture and heat. If the exhaust air of the drying room is first discharged to the operating room and then to the outside, it will affect the temperature and humidity of the studio. Connect the drying room exhaust system to the oven exhaust system, and set up a three-way pipe valve. The valve switch is interlocked with the oven's moisture exhaust, that is, when the moisture exhaust valve is opened, the exhaust port is closed. At this time, the hot and humid exhaust air of the drying room will not affect the temperature and air distribution of the drying room studio. When the aluminum-plastic packaging machine is working, the smell of PVC burnt is generated, so the exhaust air is set up, and the exhaust port is located above the heat-sealing position of the aluminum-plastic packaging. 4. The main function of the corridor for visiting the clean workshop is the passage of people and logistics, and it is also to ensure the smooth flow of fire safety passages; to make the clean area have a certain buffer with the outside world to ensure the cleanliness of the production area; as a visiting corridor, it should be used for visiting will not affect production. Moreover, the setting of clean corridors makes it possible to use heating for heating, which protects the clean area and avoids condensation on the interior walls in winter. Because the clean area is close to the outer wall, if there are no windows, it will affect the lighting of the room; if there are double-layer windows, no matter how airtight it is, dust will come in, and the cleaning of the windows will also be a problem. Therefore, the setting of the visiting corridor is more important. In the design of the clean workshop, the width of the corridor is set to 3m and the height is 2.7m. For the specific location layout, see the workshop floor plan. Because the inner surface of the building will be gray even if it is not collided, so to control the indoor cleanliness, the factors of the dust generation of the interior finishing materials should also be considered: the floor of the corridor is made of terrazzo and other materials with good integrity, and added Thick backfill, improve the cement grade, and if necessary, can also configure steel bars, add a waterproof layer, etc. to prevent ground cracking and moisture return. Latex paint (styrene-acrylic paint) can be used for wall and ceiling finishes. In addition to the selection of decorative materials with a small amount of dust, it is also necessary to reduce the parts on the inner surface of the building that are prone to dust accumulation, and easy cleaning is also an important purification measure. In the corridor design, the windows are not provided with sills, the window cabinets are flush with the wall, and the dust-accumulating platform is set at a 15-degree slope to avoid dust accumulation. Do not protrude from the wall roots, curbs, etc. on the wall. The junction of wall, top and ground should have a certain arc (half length is 20-50mm).
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