Design and selection of purification workshop equipment
Design and selection of purification pharmaceutical cleanroom equipment
The equipment in the purification workshop should be reasonably designed to avoid the formation of dead corners that are not easy to clean. The equipment must be processed with correct welding, polishing and passivation processes; the surface of the equipment in direct contact with the material should be smooth and clean to reduce the formation of biofilms on the inner wall of microorganisms And the risk of contamination, but also...
Text label: purification workshop design, purification workshop equipment selection, purification workshop engineering
Design and selection of purification workshop equipment
The equipment in the purification pharmaceutical cleanroom should be reasonably designed to avoid the formation of dead corners that are not easy to clean. The equipment must be processed with correct welding, polishing and passivation processes; the surface of the equipment in direct contact with the material should be smooth and clean to reduce the formation of biofilms on the inner wall of microorganisms The risk of contamination is also conducive to the cleaning, disinfection and sterilization of the equipment; the smoother the inner wall surface, the less time it takes to achieve the same cleaning and sterilization effect. Pollution; for the selection of stainless steel materials, it is necessary to comprehensively consider factors such as the corrosion of the medium, material processing performance, and process requirements. Equipment, containers and tools for the production of sterile drugs should preferably be made of high-quality stainless steel materials with low carbon content, such as 316L, stainless steel, etc.; including storage tanks and piping systems for water for injection and pure steam systems, equipment and containers for water for injection and piping systems, equipment, storage tanks and piping that require steam sterilization, steam heating drying ovens, drying ovens with Class A unidirectional flow protection, etc.
The fermentation tank and reaction tank used in production are waiting for stirring equipment. If the sealing is not good, the leakage of lubricating oil and coolant will cause pollution. Therefore, a reliable sealing method must be adopted to prevent pollution caused by leakage. Equipment that has moisture, hot gas or dust and needs to be directly discharged outdoors. In order to prevent the exhaust air from being poured back into the equipment and causing pollution, it is necessary to set up anti-backflow measures such as primary and medium-efficiency filters. It is too ideal, so it should not be used as an anti-backflow device for the air outlet of the equipment; in order to ensure the quality of sterile products, the structure and materials of the production equipment that are in direct contact must be able to withstand the corresponding sterilization conditions without causing structural deformation. Material deformation and other adverse consequences, such as the use of thermal sterilization, the equipment should be able to withstand high temperature and high pressure, such as VHP sterilization or gamma ray sterilization, the equipment material itself should not be deformed or produce chemical reactions and other consequences. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for purification workshops and purification plants.
Pharmaceutical purification workshops have high requirements on environmental parameters such as temperature and humidity, and belong to high-energy-consumption production buildings. Although the energy consumption factor of building envelope structure accounts for a small proportion of total energy consumption, it can improve the energy consumption of outer envelope structure. Thermal performance has positive significance for ensuring environmental parameters and saving energy; the area of u200bu200bpreparation workshops is large, mainly single-layer and multi-layer, the roof area is relatively large, and the body shape coefficient is relatively large, so special attention should be paid to the roof and exterior walls The technical interlayer and technical channel are mainly used to install air ducts, air filters, process pipes, lamps and other public works pipelines and other facilities. The technical channel is provided with access doors, which should be opened to non-clean areas. When it must be opened to the clean area, a suspended ceiling should be installed in the technical passage, and the interior decoration standard should be consistent with the requirements of the clean area. The layout of the purification workshop is generally connected by passages to each functional room. The passage in the clean area should have an appropriate width. The net width of the logistics passage should not be less than 1.4m, and the net width of the personnel passage should not be less than 1.1m. In addition to meeting the material transportation during production, the width of the aisle should also be Factors such as equipment installation, handling requirements during maintenance, and personnel evacuation should be considered.
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SUZHOU PHARMA MACHINERY CO.,LTD.’s purpose is to create superior value for our customers, employees, communities and investors through the production, conversion, delivery and sale of energy and energy services.
The rising extraction machine consciousness observed worldwide are expected to be key factors driving the demand for extraction machine CUSTOM SOLUTION SERVICES.