How to deal with the problem of dipping in the tablet press_Tablet Press_High Speed_Single Punch_Double Punch_Flower Basket_Multifunctional Rotary Tablet Press PHARMA

Binder punching means that the fine powder on the surface of the tablet is adhered by the punch and the die when the tablet is pressed, so the tablet surface is not only smooth, but also the uneven punch is more likely to stick. What causes this phenomenon? How to deal with this situation to get good results in order to use the tablet press better?

1. The surface of the punch is damaged or the surface finish is reduced. It may also contain anti-rust oil or lubricating oil, and the surface of the new mold is rough or the lettering is too deep and angular. The punch can be wiped clean and replaced with a substandard mold, or rubbed with a small amount of liquid paraffin on the surface of the lettering punch to lubricate the surface. In addition, if it is caused by mechanical heating, the cause of repair should be checked.

2. The engraving and punching character design is unreasonable. Replace the tablet press punch or change the character design accordingly.

3. The water content of the granules is too much or the granules are not dry and moist, causing the tablet press to stick. Solution: Control the moisture content of granules within the range of 2%~3%, and strengthen the inspection of dry food.

4. The amount of lubricant used is insufficient or improperly selected, and there are too many fine powders. Appropriately increase the amount of lubricant in the tablet press or replace with a new lubricant to remove excess fine powder.

5. The difference in the fineness of the original excipients leads to uneven mixing or inappropriate mixing time. Solution: While mastering and controlling the mixing time, crush and sieve the raw and auxiliary materials so that the fineness meets the quality requirements of the variety.

6. Due to the quality of the adhesive, the adhesive concentration is low or the adhesion is poor. Too much fines (more than 10%) and sticking. Solution: Sieve fine powder with 40 mesh sieve, re-granulate, dry, granulate, then blend the whole batch and press.

7. Adhesion due to the raw material itself (such as hygroscopicity). Solution: Add a certain amount of absorbent (such as adding 3% calcium hydrogen phosphate) to avoid adhesion.

8. The ambient humidity is too high, and the humidity is too high to reduce the ambient humidity.

9. If the operating room is too high, it is easy to produce viscous punches. Attention should be paid to reducing the operating room temperature.

Tablet presses are mainly used for tablet process research in the pharmaceutical industry. The tablet press is an automatic continuous production pharma machinery that presses the granules into a round irregular shape with a diameter not greater than 13mm, and with characters and symbols. Tablet presses can be divided into single-punch presses and multi-punch rotary presses. tablet.

The single punch presses the tablet through the relative movement of the upper punch and the lower punch of the cam linkage mechanism. The multi-punch rotary tablet press has multiple pairs of punches, which are set on the working turntable in a circular shape, and the tail of each punch is controlled by a fixed lifting rail. Whether it's pharma machinery or people needing to shelter in place, just know how your tablet is maintained:

1. Regularly check the tablet press 1-2 times a month. These products include worm gears, worms, bearings, pressure rollers, crankshafts, upper and lower guide rails, etc. Some of them are flexible and wear-resistant, and defects should be repaired in time.

2. The place of use should be cleaned frequently, especially for pharmaceuticals and edible tablets, where dust is flying.

3. The maintenance of the mold should be placed in a metal box with a cover, so that the mold is completely immersed in the oil, and kept clean, free from rust and scratches, it is best to customize the iron box, and install a box in each specification to avoid mistakes Operate and help master damage.

4. When the tablet press is in use or stops working, please remove the residual powder to remove the residual powder in the machine name. If it is not used for a long time, the mold must be removed and the machine should be wiped down. Cover the oil with a cloth.

In the maintenance of a tablet press, it is first necessary to start with the components. Only when the components are safe can the tablet press be better protected to prolong the life of the tablet press.

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