It is more scientific and reasonable for the tablet press to maintain the total amount
Tablet press lamination means that two pieces are folded into one piece. The sheet sticks to the upper punch due to factors such as sticking punch or upper punch curling. At this time, the particles are filled in the die hole and pressed again to form a stack, or because the rising position of the lower punch is too low, the sheet cannot be ejected immediately. , and at the same time, the particles are added to the die hole and repeatedly pressurized. Rolling into laminates makes the tablet press vulnerable to damage. The problem of sticking and punching should be dealt with and supporting facilities for punches, improving the reliability of cold punching dies, and eliminating common faults in the tablet press. The reason and solution of the loose tablet of the tablet press are as follows: the loose tablet refers to that after the sheet is rolled, the hardness is insufficient, and the surface layer has pits, and it will break when it is gently pressed with fingers. Not enough pressure. Solution: Increase the pressure. However, for some special purposes, the specified pressure is relatively large for a large area, and if the pressure is specified to meet the pressure limit of the tablet press or exceed the pressure limit, a tablet press of the corresponding size with a large pressure must be ordered. The force duration is too little, and the speed ratio is too fast. Correspondingly increase the stress duration, increase the prestress tension, and reduce the speed ratio. The length of the upper punch of the multi-punch tablet press is different. Solution: Adjust the punch needle. The flexible punching needle produces loosening. Start tightening. Insufficient particle size of the drug, fibrous or elastic drug or crude oil with a large proportion and uneven mixing. It can be overcome by crushing the drug through a 100-mesh sieve, using a highly viscous adhesive, moderately increasing the pressure of the tablet press, and increasing the raw material oil drug adsorbent for sufficient stirring. Due to insufficient or unreasonable selection of binder or wetting agent, the granular material is loose or the particle size is uneven, and the sand and fine particles are stratified. It can be overcome by choosing an appropriate binder or increasing the amount of use, improving the granulation process, mixing more soft materials, and mixing uniform particles. The moisture content of the granules is too low, and the granules that are too dry have great ductility. Drugs with carboxyl groups lose more carboxyl groups during the drying process of the granules, making the granules crisp and easy to loosen. Therefore, when granulating, the moisture content of the granules should be controlled according to different types. If the granules are too dry, spray them with appropriate amount of dilute ethyl acetate (50%-60%), stir and press into candies. properties of the drug itself. Although the densely pressed sheet has strength, it cannot withstand impact and vibration. Such as soda flakes, etc. are usually easy to cause loose flakes; the relative density is small, the flowability is poor, and the compressibility is poor, so it is re-granulated. The fluidity of the particles is poor, and the particles filling the holes in the die are uneven. There are relatively large pieces or particles, and debris block the scraper and the material opening, affecting the filling amount. The particles in the hopper are sometimes more and sometimes less. Granules should be added frequently to maintain the total amount in the silo.