Laboratory Design and Basic Requirements

Design and Basic Requirements

The location, design and construction of the laboratory shall comply with the regulations and requirements of national and local construction planning, biosafety, environmental protection and technical specifications; the laboratory design shall fully consider issues such as work convenience, reasonable procedures, and personnel comfort; Consider Biosafety Lab Ground...

Text label: laboratory design and installation, basic requirements for clean laboratory

Lab Design and Basic Requirements

The location, design and construction of the laboratory shall comply with the regulations and requirements of national and local construction planning, biosafety, environmental protection and technical specifications; the laboratory design shall fully consider issues such as work convenience, reasonable procedures, and personnel comfort; Considering the special requirements of cleaning, disinfection, anti-leakage, anti-dust, etc. on the floor, wall, ceiling, pipe, cabinet, etc. of the biosafety laboratory, comprehensively consider from the aspects of energy saving, environmental protection, safety and economy ;Indoor environmental parameters such as temperature, humidity, illuminance, noise and cleanliness in the laboratory should meet the work requirements, as well as the requirements of personnel comfort and hygiene; corridors and passages should not hinder the passage of people and items; the door of the room should be accessible. View windows and install door locks as needed. The door locks should be easy to open quickly inside. Appropriate warning and access restriction measures, such as warning signs, should be taken according to the needs of the room or pharma machinery in different states such as use, deactivation, disinfection, and maintenance. , lights and access control, etc.; should be specially designed to ensure the safety of storage, transfer, collection, processing and disposal of test samples and materials.

The BSL-1 laboratory shall provide sufficient space for the installation, cleaning and maintenance, and safe operation of laboratory equipment; sufficient space and cabinets to place laboratory equipment and items; food, water and rest The site should be located outside the work area of u200bu200bthe laboratory; laboratory walls, ceilings and floors should be smooth, easy to clean, leak-proof and resistant to chemicals and disinfectants, the floor should be non-slip, and carpets and curtains should not be laid in the laboratory ; Cabinets, tables and chairs, etc. should be stable and sturdy, the corners should be smooth, and the experimental table should be waterproof, and can withstand heat, organic solvents, acid and alkali and other chemical agents; laboratory equipment and tables should be reasonably placed according to the nature and process of work. Cabinets, items, etc., to avoid mutual interference and cross-contamination, there should be sufficient distance between the cabinet and the equipment to facilitate cleaning; the pharma machinery should be equipped with a hand-washing basin, and the tap switch should be non-manual and should be set near the exit; The door should have visible windows and can be locked, and should meet the appropriate fire protection level. The door lock and the opening direction of the door should not hinder the escape of indoor personnel; the operation involving infectious, irritating or corrosive substances should be provided within 30m. If the risk is high, an emergency sprinkler should be installed; if high-pressure gas and combustible gas are used, safety measures should be taken; there should be a reliable and sufficient power supply to ensure the safety of electricity use; emergency lighting should be installed, and appropriate The installation location is to ensure that personnel leave the laboratory safely; sufficient power sockets should be provided to avoid the use of common power sockets for multiple devices, a reliable grounding system should be provided, and leakage protection devices or monitoring and alarm devices should be installed at key nodes; water supply pipelines A backflow preventer or other effective backflow prevention device should be installed, the water supply and drainage system should not leak, and the water should be designed to prevent backflow; it should be equipped with appropriate emergency equipment, communication equipment, and appropriate disinfection and sterilization equipment if necessary. . Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for laboratories and clean rooms.

The door of the main entrance of the BSL-2 laboratory and the door of the experimental room where the biological safety cabinet is placed should be able to close automatically. The door of the main entrance of the laboratory should have access control measures; there should be conditions for storing spare items outside the working area; Equipped with eye wash devices in the laboratory work area, and eye wash devices should be provided in each workroom if necessary; biosafety cabinets should be installed and used according to the requirements of product design and instruction manual; if a biosafety cabinet with duct exhaust is used, it should be It is discharged from the pipes independent of other public ventilation systems of the building; the reinforced BSL-2 laboratory should include a buffer room and a core work room; the buffer room can double as a protective clothing changing room, and a preparation room and a washing room can be set up if necessary; the buffer room The doors in the room should be able to be interlocked. If an interlock door is used, an emergency manual interlock release switch should be set near the interlock door; the air supply and exhaust ports in the core work room should be arranged in accordance with the principle of directional airflow, which is conducive to reducing Vortex and airflow in the room; the air pressure in the core work room should be negative pressure relative to the adjacent area, and the pressure difference should not be less than 10pa. A pressure display device to display the negative pressure of the room should be installed at a prominent position at the entrance of the core work room; The stability of laboratory pressure or pressure gradient should be ensured by means of air supply and exhaust devices, such as exhaust fans or ventilation fans or automatic control measures; laboratory exhaust air should be interlocked with the supply air, and the exhaust air should be opened before the supply air, and then after the supply air. The wind should be closed; the temperature of the core work room should be maintained at 18-26°C, and the noise should be lower than 68dB; the laboratory should be equipped with an internal exhaust pressure steam sterilizer and other applicable disinfection equipment.

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