Layout and construction of sterile injection purification plant
Layout and construction of sterile injection purification plant
The production process of freeze-dried powder injection in the purification plant includes glass bottle cleaning, sterilization and drying, batching, filling, freeze-drying, rubber stopper, rolling and sealing aluminum cover, semi-finished product inspection, labeling and other processes; freeze-drying equipment It is a very important pharma machinery in production. Injectable injection...
Text label: Sterile injection purification plant, design layout and construction
Layout and construction of sterile injection purification plant
The production process of freeze-dried powder injection in the purification plant includes glass bottle cleaning, sterilization and drying, batching, filling, freeze-drying, rubber stopper, rolling and sealing aluminum cover, semi-finished product inspection, labeling and other processes; freeze-drying pharma machinery It is a very important pharma machinery in production. According to the characteristics of the product, four different filling systems can be selected for the filling of injections: rotary piston pump, rotary diaphragm pump, time pressure filling system, and mass flow system. The commonly used rotary piston pump is made of stainless steel or ceramic materials. Its structure consists of three parts: rotating piston, pump body and moving piston; personnel, equipment and materials should enter the clean area through the corresponding air lock room, and should maintain proper cleanliness. The air supply must be filtered by the filter. Efficiency must meet specified standards.
Air flow packing machine uses vacuum quantitatively, and blows compressed air into vials through purification and drying. The compressed air system consists of several parts. The ultrasonic bottle washing machine consists of a pool, a washing part and an air drying part. The washed vials should be dried and sterilized as soon as possible to prevent pollution. The sterilization and drying equipment includes cabinet type and tunnel type sterilization oven. The stopper system includes rubber stopper oscillator, vertical track for lower stopper, stopper mechanism, etc. The sterile rubber stopper is in the oscillator. , at the end of the track, the suction rod uses vacuum to suck the rubber stopper, remove the possible rubber powder and position the rubber stopper, and then push the rubber stopper into the gripper of the stopper mechanism through the swing arm. When the gripper turns to the lowest position , the stopper is spun onto the vial mouth just reaching here. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for purification plants and sterile plants.
The conveying system of the purification plant provides vials for sub-packaging and corking, including bottle supply turntable, mesh belt, chain drive, track baffle, bottle dial, etc. The track baffle and pallet can be adjusted according to the vial specifications to prevent jamming Bottles and broken bottles, the smooth bottle feeding system will ensure the smooth progress of production. After the powder is put into the bottle and the rubber stopper is plugged, in order to ensure that the bottle is sealed and airtight, an aluminum cap must be rolled on the rubber stopper. The powder needle capping machine can be divided into single-knife and multi-knife types according to the working parts. The method can be divided into rolling type and bayonet type, among which the rolling type has two forms: the bottle does not move and the bottle follows.
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