Main Factors Affecting Tablet Friability
Friability has been included in the pharmacopoeia tablet inspection project for a long time, but it has not become a mandatory inspection item for tablets. We can examine why friability inspection has not been a A mandatory inspection item for tablet quality inspection. In the early days, many tablets (such as 100 tablets) produced by pharmaceutical factories were put into glass or plastic bottles together. If these tablets are not hard enough, they will be damaged during transportation and storage. Vibration may cause friction and collision between tablets and between tablets and the bottle, resulting in reduced tablet weight, reduced drug loading per tablet, and reduced curative effect. In order to prevent this from happening and control the quality of medicines, the Pharmacopoeia will formulate a friability inspection method to