Oral solid preparation GMP workshop
Oral solid preparation GMP pharmaceutical cleanroom
(1) Packaging equipment for oral solid preparation GMP pharmaceutical cleanroom
Oral solid conventional packaging equipment can be divided into bottle packaging equipment, aluminum-plastic packaging equipment and bag packaging equipment.
①Bottle packaging equipment mainly includes bottle unscrambler, automatic counting machine, capping machine, sealing machine, labeling machine...
Text label: Oral solid preparation GMP workshop, preparation workshop purification equipment
Oral solid preparation GMP workshop
(1) Packaging equipment for oral solid preparation GMP workshop
Oral solid conventional packaging equipment can be divided into bottle packaging equipment, aluminum-plastic packaging equipment and bag packaging equipment.
①Bottle packaging equipment mainly includes bottle unscrambler, automatic counting machine, capping machine, sealing machine, labeling machine and other equipment. The following takes the packaging equipment in tablet production as an example to introduce.
a. The bottle unscrambler can automatically unscrew the bottle by rotating, and then send the neat bottle packaging material to the next process. Generally include: bottle positioning device to ensure the correct positioning of the bottle, after passing through the positioning turntable and the bottle feeding and knocking device, there is only one bottle in the positioning groove; automatic air pressure bottle blowing device, the air pressure is adjustable, which can ensure that the reverse bottle is blown out, The positive bottle can pass smoothly and enter the slideway; the photoelectric frequency conversion device, the clutch is sensitive, the automatic opening and stopping of the bottle is correct, the bottle is blocked and the bottle is stopped and the bottle is started.
b. The tablet counting machine is automatically controlled by PLC, the tablet counting device is automatically activated when the bottle is supplied, and the tablet can be accurately put into the bottle. The counting methods generally include disc counting and photoelectric counting. When the quantity does not match the set quantity, the program can automatically control the bottles to be rejected. The equipment automatically stops the counting device when there is no bottle, stops when the bottle is blocked, and starts the bottle feeding.
c. The capping machine adopts PLC control with stepless speed regulation. Caps can be automatically arranged, capped, and capped. The capping tightness program can be adjusted. The equipment will automatically shut down when there is no cap or bottle. The bottle will be automatically turned on, and the bottle will be blocked. The bottle will be automatically rejected. .
d.Sealing Machine The automatic sealing machine can automatically seal the aluminum foil in the bottle cap on the bottle, the sealing temperature is adjustable, no aluminum foil in the bottle cap is removed, and the aluminum foil is counted.
e. Labeling Machine The label of a tablet refers to the content printed or affixed on the tablet package, and the labeling machine is the equipment that completes the labeling on the tablet package.
The working principle of the automatic labeling machine: the bottle is sent to the feeding device, and the bottle is separated at a fixed interval by the feeding device, and then the bottle is accurately sent to the conveyor chain. At the same time, the label is printed, the printing information is detected, and the label is peeled off. After that, the bottle roll device of the equipment is completely labelled. The equipment has the function of rejecting missing labels and printing information that is inconsistent with the set standard. Zhongjing Global Purification can provide supporting services such as consultation, planning, design, construction, installation and transformation of preparation workshops and sterile rooms.
②Aluminum-plastic packaging equipment The main equipments are blister packaging machine and double aluminum foil packaging machine.
a.Blister packaging machine The general process of blister packaging machine:
Film conveying→heating→forming→filling→heat sealing→printing→punching
Blister packaging machine is a high-efficiency packaging equipment that can complete the functions of PVC sheet thermoforming, tablet filling, heat sealing with aluminum foil, printing, punching and conveying. Manual or automatic equipment checks for defects or missing grains, etc. If an imaging detection system is used to detect the filled tablet plates, all tablet plates with missing grains, half grains and inconsistent colors can be eliminated to better ensure product quality. . The equipment can be used to package oral solid products of various geometric shapes, such as plain tablets, sugar-coated tablets, capsules, drop pills, etc. Commonly used blister packaging machines include drum blister packaging machines, flat blister packaging machines and roller blister packaging machines.
b.Double aluminum foil packaging machine The packaging material used in the double aluminum foil packaging machine is coated aluminum foil. Because the coated aluminum foil has good air tightness, moisture resistance and light protection, it is required for sealing and light protection. Tablets, pills and other packaging are more advantageous. The equipment generally adopts frequency conversion speed regulation, and the cutting size can be set arbitrarily. It can print on the outside of two aluminum foils at the same time, and can realize the continuous completion of filling, heat sealing, indentation, printing batch number, cutting and other processes. It has a packaging material shortage detection device and the function of random automatic detection and automatic rejection of missing tablets and missing tablets, which can better ensure product quality.
③Bag Packaging Equipment Bag filling and sealing packaging machine is often used for the packaging of granules, tablets, powders and fluid and semi-fluid materials. Commonly used packaging materials are single film and composite film.
The process of bag making, filling, sealing and packaging machine includes bag making, measuring and filling, sealing, cutting, testing and counting.
After the packaging material is made into a bag of a certain shape, the product is filled into the prepared bag according to a certain amount, and then sealed. After completion, the sealed bag is cut into individual packaging bags, and the packaging bags are detected and counted.
are present in just about every facet of modern life.
If you would like to learn more about , be sure to visit PHARMA MACHINERY for more information!
You can get more information from PHARMA MACHINERY for on sale. welcome to visit us and send your inquiry!
SUZHOU PHARMA MACHINERY CO.,LTD. will give you a suitable price for purchasing CUSTOM SOLUTION SERVICES.