Powder Direct Compression Process_Tablet Press_High Speed_Single Punch_Double Layer_Flower Basket Type_Multifunctional Rotary Tablet Press PHARMA

The editor of PHARMA will share with you a brief analysis of the causes and solutions of the problem of tablet slivers in tablet presses

Powder (granule) forming and tableting refers to filling powder or granular materials into the middle die hole and pressing the upper punch and the lower punch in opposite directions to form tablets. In the pharmaceutical process of traditional Chinese and Western medicine, the phenomenon of tablet splitting is very common. Tablet press machine During the process of compressing tablets, the waist of the pressed tablet is often cracked, and the top is cracked and capped. Its causes and solutions are as follows:

1. The material is dried after wet granulation. If it is too dry or the material loses too much crystal water, the compressibility is poor. It can be compressed by spraying an appropriate amount of alcohol or mixing it with a material with a large water content. .

2. The pressed material has too much fine powder, the particles are too thick or too fine, or the material is needle-shaped or flake-like crystallized, and the crystallization is too large, so that the adhesive does not enter the interior of the crystal, resulting in splitting.

3. Too much oil in the raw material or too much fiber content in the raw material can be overcome by adding absorbent or powdered sugar.

4. The punching die of the tablet press does not meet the requirements, the wear inside the middle die is serious, resulting in the diameter of the middle hole of the middle die being larger than the diameter of the mouth, and the installation of the upper punch and the middle die does not match, resulting in uneven pressure, and the punching nails have inward curling Phenomena may cause cracks.

5. The running speed of the machine is too fast and the pressure of the machine is too high, so that the air in the granular raw materials cannot be discharged in time. It can be solved by increasing the pre-compression function of the tablet press, adjusting the pressure and the speed of the tablet press.

It is understood that there are various types of tablet presses in the Chinese market at present, and the pharma machinery for fine powder tablet pressing is also constantly updated and evolved. The ZPW17E rotary tablet press produced by our company is professional for double-layer tablets and fine powder tablets. And high-yield small pharma machinery R & D and production, please consult our company hotline: 021-57667108 for details.

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