What are the usage specifications of the purification workshop?1

In industry or medicine, in order to control indoor pollution, we need to build purification workshops. Cleanrooms filter, distribute and optimize air. The concentration of airborne particles can be controlled to achieve the appropriate level of particle cleanliness. Due to factors such as its regional environment and degree of purification, purification workshops are also divided into multiple levels. So what are the specifications for the use of purification workshops? One: The operating time of the purification system is stipulated, and the purification system is required to be turned on for at least 1 hour before each experiment, and the purification bench and the ultraviolet lamp are turned on at the same time. 2: Basic requirements for items entering the purification pharmaceutical cleanroom (sterile room): All items entering the purification workshop (sterile room) must be disinfected and sterilized on the external surface in the first buffer room, and then pass through the logistics buffer room and the input window for more than 1 Hours, after drying with sterile air, sent to the sterile room. Pay attention to fibers, and dust-prone items should not be brought into the purification pharma machinery. The fixed items in the sterile room shall not be removed at will. 3. Requirements for personnel entering the purification workshop (sterile room): pharma machinery personnel entering the purification pharmaceutical cleanroom (sterile room) are not allowed to make up, watches, rings and other jewelry; do not eat, chew gum. After cleaning your hands, go to the first buffer room to change your clothes. At the same time, put on sterile isolation slippers, take off your coat, disinfect your hands with disinfectant, put on sterile gloves, put on a sterile hood (do not expose your hair and clothing), and put on a sterile mask. Then, change or put on a second pair of sterile gloves and a second pair of sterile isolation slippers when entering the second buffer chamber. Then enter the sterile room after 30s air shower in the air shower. Four: Temperature and humidity observation requirements: Observe whether the temperature and humidity displayed on the thermometer are within the specified range, and record it as the original data of the experiment. If a problem is found, the reason should be found out in time, the pharma machinery supervisor should be reported in time, and the reasons and results of the report should be recorded. Five: Counting of sedimentation colonies and determination of planktonic bacteria: In each experiment, the microbial sedimentation colonies are counted on the operating room and laminar flow platform, and the results are recorded in the experimental report as the original data of the experimental environment. Once a week, or if necessary, perform a sterility check, measure the planktonic bacteria in the operating room and the clean bench in each experiment, record the results in the use register, and record the experimental report as the original data of the experimental environment. 6. Disinfection requirements: use 0.1% sanjierzil or 2% cresol solution or other suitable disinfectant every week and before each operation in the sterile room (commonly used disinfectants are: 5-20 times diluted iodophor aqueous solution, 0.1% Xinjieermin solution, 1:50 84 disinfectant, 75% ethanol solution, 3% iodine solution, 5% carbolic acid (Lysol) disinfectant, 2% glutaraldehyde aqueous solution, paraben ethanol disinfectant (prescription: parahydroxyl Methyl benzoate 21.5g; Propylparaben 8.6g, 75% ethanol 10ml, etc. The type of disinfectant used and its use should be verified for effectiveness before use, and the type of disinfectant should be replaced regularly.) Wipe the operating table and Dead corners that may be contaminated. The method is to use sterile gauze impregnated with disinfectant to clean the entire inner surface, top surface, sterile room, people flow, logistics, buffer room floor, transfer window, door handle of the ultra-clean bench. The cleaning and disinfection procedures should be from the inside to the In addition, from the high clean area to the low clean area. Gradually exit the clean area. Then turn on the sterile air filter and ultraviolet sterilization for 1-2 hours to kill the remaining microorganisms. The editor of the company in the purification pharmaceutical cleanroom reminds that after each operation, also Wipe the workbench with the above disinfectant to remove indoor moisture and sterilize with ultraviolet light for 30 minutes.

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